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Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies
The odds of dying from coronary heart disease (CHD) and other chronic ailments may be stacked against lovers of foods loaded with trans-fatty acids.
This study performed a meta-analysis on data drawn out from 18 studies that evaluated the connection between high fat diets and mortality risk. More than 300,000 participants volunteered for these studies.
Researchers identified a surge in coronary heart disease (CHD) and total mortality risk among participants at the top of the trans-fatty acid-rich food consumption ladder. This study is one of the many studies that have provided evidence that consistent ingestion of foods ladened with trans-fatty acids may increase death toll from coronary heart disease and other ailments.
Research Summary Information
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2015
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Russell J de Souza, Andrew Mente, Adriana Maroleanu, Adrian I Cozma, Vanessa Ha, Teruko Kishibe, Elizabeth Uleryk, Patrick Budylowski, Holger Schünemann, Joseph Beyene, Sonia S Anand
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Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Chanchlani Research Centre, McMaster University, Hamilton, ON, Canada Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Chanchlani Research Centre, McMaster University, Hamilton, ON, Canada Population Health Research Institute, Hamilton Health Sciences, Hamilton, ON, Canada. Chanchlani Research Centre, McMaster University, Hamilton, ON, Canada. Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada anands@mcmaster.ca. Scotiabank Health Sciences Library, St Michael's Hospital, Toronto, ON, Canada. Hospital Library and Archives, Hospital for Sick Children, Toronto, ON, Canada. Clinical Nutrition and Risk Factor Modification Center, St Michael's Hospital, Toronto, ON, Canada. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Department of Medicine, McMaster University, Hamilton, ON, Canada. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Chanchlani Research Centre, McMaster University, Hamilton, ON, Canada. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Chanchlani Research Centre, McMaster University, Hamilton, ON, Canada Population Health Research Institute, Hamilton Health Sciences, Hamilton, ON, Canada Department of Medicine, McMaster University, Hamilton, ON, Canada anands@mcmaster.ca.
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