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Investigating Causal Associations of Diet-Derived Circulating Antioxidants with the Risk of Digestive System Cancers: A Mendelian Randomization Study

Imbibing the habit of eating foods loaded with retinol and vitamin C regularly may help shield us from developing pancreatic and colon cancer.

This study determined the level of protection offered by dietary antioxidants against cancers affecting the digestive system. Researchers collated and evaluated dietary and health information obtained from the UK Biobank and FinnGen database. 

Data analysis revealed that strict adherence to diets centered around the consumption of foods rich in antioxidants, such as retinol and ascorbic acid (vitamin C), brightened an individual's chances of warding off pancreatic and colon cancer respectively. The findings of this study further affirmed that upping the intake of retinol and vitamin C from dietary sources may help thwart the development of pancreatic and colon cancer.

Research Summary Information

  • 2022
  • Xuening Zhang, Hao Zhao, Jinyu Man, Xiaolin Yin, Tongchao Zhang, Xiaorong Yang, Ming Lu
  • Department of Epidemiology and Health Statistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China. Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan 250012, China. Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Clinical Research Center, Qilu Hospital of Shandong University, Jinan 250012, China.
  • Yes, Free full text of study was found:
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