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Association of prebiotic fiber intake with colorectal cancer risk: the PrebiotiCa study

Promoting the consumption of plant foods loaded with the prebiotic fiber raffinose and stachyose may help reduce the incidence of colorectal cancer.

This study was undertaken to assess the link between adhering to a high fiber diet and the likelihood of being diagnosed with colorectal cancer. Researchers tracked the frequency of intake of fiber-rich foods among 1,953 patients with colorectal cancer patients and 4,154 individuals without this malignancy. 

Regular ingestion of foods rich in the prebiotic fiber raffinose and stachyose was found to cut down down the risk of colorectal cancer dramatically in this study. Evidence from this study support the consumption of plant foods high in the prebiotic fiber raffinose and stachyose as part of dietary approach to curb the onset of colorectal cancer.

Research Summary Information

  • 2023
  • Federica Turati, Federica Concina, Marta Rossi, Federica Fiori, Maria Parpinel, Martina Taborelli, Attilio Giacosa, Anna Crispo, Eleonora Pagan, Valentina Rosato, Eva Negri, Carlo La Vecchia
  • Unit of Medical Statistics and Biometry, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. federica.turati@unimi.it. Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy. federica.turati@unimi.it. Clinical Epidemiology and Public Health Research Unit, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Trieste, Italy. Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy. Department of Medicine, University of Udine, Udine, Italy. Unit of Cancer Epidemiology, CRO Aviano National Cancer Institute, IRCCS, Aviano, Italy. Department of Gastroenterology and Clinical Nutrition, Policlinico di Monza, Monza, Italy. Epidemiology Unit, Istituto Tumori "Fondazione Pascale IRCCS", Naples, Italy. Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy. Unit of Medical Statistics and Biometry, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
  • Yes, Free full text of study was found:
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