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Prebiotics and the Risk of Upper Digestive Tract and Stomach Cancers: The PrebiotiCa Study

Filling our plates with plant foods loaded with the prebiotic fiber raffinose may boost our chances of warding off stomach cancer.

This study explored the link between high dietary ingestion of prebiotic fiber and the occurrence of cancerous cells and tumors in the mouth, pharynx, esophagus, and stomach. More than 5,000 persons enrolled for this study and provided information about their food choices and cancer diagnosis status.

Researchers noticed that increased intake of plant foods rich in the prebiotic fiber raffinose diminished the risk of developing stomach cancer. The results of this study showed that regular consumption of raffinose-containing plant foods may help thwart the development of stomach cancer.

Research Summary Information

  • 2023
  • Federica Turati, Federica Concina, Paola Bertuccio, Federica Fiori, Maria Parpinel, Werner Garavello, Anna Crispo, Massimo Libra, Eva Negri, Diego Serraino, Carlo La Vecchia
  • Branch of Medical Statistics, Biometry, and Epidemiology "G.A. Maccacaro," Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address: federica.turati@unimi.it. Institute for Maternal and Child Health, IRCCS "Burlo Garofolo," Trieste, Italy. Branch of Medical Statistics, Biometry, and Epidemiology "G.A. Maccacaro," Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy. Department of Medicine-DAME, University of Udine, Udine, Italy. School of Medicine and Surgery, University of Milano-Bicocca, Italy; Department of Otorhinolaryngology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italia. Epidemiology Unit, National Cancer Institute "Pascale Foundation" IRCCS, Naples, Italy. Laboratory of Translational Oncology & Functional Genomics, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. Unit of Cancer Epidemiology, CRO National Cancer Institute, IRCCS, Aviano, Italy. Branch of Medical Statistics, Biometry, and Epidemiology "G.A. Maccacaro," Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Yes, Free full text of study was found:
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