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Lignan Intake and Risk of Coronary Heart Disease

Greater consumption of lignan-rich foods may improve an individual's likelihood of fending off coronary heart disease (CHD).

This study evaluated the influence of dietary intake of lignan on the burden of coronary heart disease (CHD) in men and women. Researchers assessed the dietary and health records of more than 200,000 US men and women. 

Data analysis revealed that participants with high rate of ingestion of lignan-containing foods had low probability of developing coronary heart disease. This study recommended the incorporation of foods rich in lignans as an integral component of a heart-healthy diet.

Research Summary Information

  • 2021
  • Yang Hu, Yanping Li, Laura Sampson, Molin Wang, JoAnn E Manson, Eric Rimm, Qi Sun
  • Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. Electronic address: yanghu@hsph.harvard.edu. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; Joslin Diabetes Center, Boston, Massachusetts, USA.
  • Yes, Free full text of study was found:
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