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Research Team that works on the Science Health Research Summaries and other research projects.

High caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women.

Regular intake of high-calorie breakfast and low-calorie dinner may promote weight loss and improve the conditions of obese women with metabolic syndrome.

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  2791 Hits

Intensive lifestyle changes for reversal of coronary heart disease.

A lifestyle that involves the regular intake of low-fat vegetarian diets, aerobic exercise, and stress reduction may improve and reverse the conditions of coronary heart disease patients.

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  2891 Hits

Vascular endothelium and human disease.

Endothelial dysfunction may be a good indicator of the presence of various diseases, such as diabetes, stroke, cancer, and atherosclerosis.

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  4362 Hits

Postprandial angina pectoris: clinical and angiographic correlations.

Postprandial angina pectoris is associated with severe coronary artery disease.

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  4633 Hits

Interactions of dietary whole grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies.

Genes may influence the plasma insulin-reducing activity of whole grains in persons of European descent.

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  • 2010
  • Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, van Rooij FJ, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, Garcia M, Anderson JS, Follis JL, Djousse L, Mukamal K, Papoutsakis C, Mozaffarian D, Zillikens MC, Bandinelli S, Bennett AJ, Borecki IB, Feitosa MF, Ferrucci L, Forouhi NG, Groves CJ, Hallmans G, Harris T, Hofman A, Houston DK, Hu FB, Johansson I, Kritchevsky SB, Langenberg C, Launer L, Liu Y, Loos RJ, Nalls M, Orho-Melander M, Renstrom F, Rice K, Riserus U, Rolandsson O, Rotter JI, Saylor G, Sijbrands EJ, Sjogren P, Smith A, Steingrímsdóttir L, Uitterlinden AG, Wareham NJ, Prokopenko I, Pankow JS, van Duijn CM, Florez JC, Witteman JC; MAGIC Investigators, Dupuis J, Dedoussis GV, Ordovas JM, Ingelsson E, Cupples L, Siscovick DS, Franks PW, Meigs JB.
  • Dupuis J, Claudia L, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Lindgren CM, Mägi R, Morris AP, Randal J, Rybin D, Johnson T, Henneman P, Gieger C, Thorleifsson G, Steinthorsdottir V, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goe A, Perry JR, Lajunen T, Grallert H, Li M, Stringham HM, Kumari M, Timpson NJ, Shrader P, Ingelsson E, Zabena C, O'Connell J, Cavalcanti-Proença C, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Sethupathy P, Andrew T, Ariyurek Y, Balkau B, Barter P, Bennett AJ, Ben-Shlomo Y, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Crawford GJ, Crisponi L, Day IN, Geus Ed, Dina C, Doney A, Egan JM, Elliott P, Erdos MR, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hingorani AD, Hofman A, Isomaa B, Jula A, Kaakinen M, Kanoni S, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Lathrop GM, Lawlor DA, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, GIANT Consortium, Global BPgen Consortium, Loos RJ, Meneton P, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Franks PW, Ebrahim S, Marmot M, Kuusisto J, Laakso M, Kao WH, Pankow JS, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright A, Stumvoll M, Campbell H, Wilson JF, Hamsten A, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma D, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I.
  • Yes, Free full text of study was found:
  1941 Hits

Intestinal microbiota metabolism and atherosclerosis.

Trimethylamine-N-oxide (TMAO), a metabolite produced by intestinal microbes, is associated with elevated atherosclerosis and cardiovascular disease risk.

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Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.

High serum and urine concentrations of TMAO, produced from intestinal microbial metabolism of phosphatidylcholine, may increase an individual’s susceptibility to adverse cardiac events and cardiovascular diseases.

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  • 2013
  • Tang WH, Wang Z, Levison BS, Koeth RA, Britt EB, Fu X, Wu Y, Hazen SL.
  • Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland 44195, USA.
  • Yes, Free full text of study was found:
  • Yes. Source of funding disclosure found
  • Supported by grants from the National Institutes of Health and its Office of Dietary Supplements (R01HL103866 and 1P20HL113452). The clinical study GeneBank was supported by grants from the National Institutes of Health (P01HL098055, P01HL076491, R01HL103931, and R01DK080732) and a Cleveland Clinic/Case Western Reserve University Clinical and Translational Science Award (UL1TR000439). Dr. Hazen was supported by a gift from the Leonard Krieger Fund. Mass spectrometry instrumentation used was housed within the Cleveland Clinic Mass Spectrometry Facility with partial support through a Center of Innovation by AB SCIEX.
  • No. Potential conflicts disclosure not found
  3799 Hits

The effect of a low-fat, plant-based lifestyle intervention on serum HDL levels and the implications for metabolic syndrome status - a cohort study.

Low-fat, plant-based diets are associated with low plasma levels of High Density Lipoprotein (HDL) and improved cardiovascular health.

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  • 2013
  • Kent L, Morton D, Rankin P, Ward E, Grant R, Gobble J, Diehl H.
  • Avondale College of Higher Education, 582 Freemans Drive (PO BOX 19), Cooranbong NSW 2265, Australia Australasian Research Institute, 185 Fox Valley Rd, Wahroonga, NSW 2076, Australia Medical Nutrition Therapy Northwest, 13568 SE 97th Ave. Suite 203 Clackamas, Oregon 97015, USA Lifestyle Medicine Institute, PO Box 818, Loma Linda, CA 92354, USA
  • Yes, Free full text of study was found:
  2403 Hits

Low-carbohydrate diets and all-cause mortality: a systematic review and meta-analysis of observational studies.

Diets low on carbohydrates may increase total mortality risk.

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  • 2013
  • Noto H, Goto A, Tsujimoto T, Noda M.
  • Department of Diabetes and Metabolic Medicine, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan. noto-tky@umin.net
  • Yes, Free full text of study was found:
  • Yes. Source of funding disclosure found
  • This study was supported by a Health Sciences Research Grant (Comprehensive Research on Diabetes/Cardiovascular and Life-Style Related Diseases H22-019) from the Ministry of Health, Labour and Welfare of Japan.
  • No. Potential conflicts disclosure not found
  2709 Hits

Whole grains are associated with serum concentrations of high-sensitivity C-reactive protein among premenopausal women.

High intake of whole grains is associated with low serum concentrations of high sensitivity C-reactive protein and improved reproductive health in pre-menopausal women.

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  2883 Hits

Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study.

High cardiovascular disease risk is associated with low carb-high protein diets.

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  • 2012
  • Lagiou P, Sandin S, Lof M, Trichopoulos D, Adami HO, Weiderpass E.
  • Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27 Athens, Greece. pdlagiou@med.uoa.gr
  • Yes, Free full text of study was found:
  • Yes. Source of funding disclosure found
  • The study was supported by grants from the Swedish Cancer Society and the Swedish Research Council.
  • No. Potential conflicts disclosure not found
  2565 Hits

Global sodium consumption and death from cardiovascular causes.

Sodium consumption above 2g per day is one of the major causes of cardiovascular-related deaths worldwide. This study examined the effect of sodium consumption on global cardiovascular mortality. Researchers analyzed dietary and clinical data obtained from subjects in 66 countries. The blood pressure and cardiovascular mortality hazard ratios were assessed in all the subjects. Researchers...

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  • 2014
  • Mozaffarian D, Fahimi S, Singh GM, Micha R, Khatibzadeh S, Engell RE, Lim S, Danaei G, Ezzati M, Powles J; Global Burden of Diseases Nutrition and Chronic Diseases Expert Group.
  • Mozaffarian D, Ezzati M, Fahimi S, Khatibzadeh S, Micha R, Powles J, Shi P, Elmadfa I, Kalantarian S, Rao M, Wirojratana P, Lim SS, Andrews KG, Engell RE, Elliott P, Brown I, Britton J, Fogarty A, Land MA, Lewis S, McKeever T, Neal B, Ocké MC, Webster J, Abbott PA, Abdollahi M, Gilardon EA, de Salud M, Ahsan H, Al Nsour MA, Al-Hooti SN, Barennes H, Barquera S, Baylin A, Becker W, Bjerregaard P, Bourne LT, Calleja N, Capanzana MV, Castetbon K, Chang HY, Chen Y, Cowan MJ, De Henauw S, Ding EL, Duante CA, Duran P, Elmadfa I, Barbieri HE, Farzadfar F, Fernando DN, Hadziomeragic AF, Fisberg RM, Forsyth SJ, Garriguet D, Gauci D, Ginnela BN, Guessous I, Gulliford MC, Hadden WC, Haerpfer C, Hoffman DJ, Houshiar-rad A, Huybrechts I, Hwalla NC, Ibrahim HM, Inoue M, Jackson MD, Johansson L, Keinan-Boker L, Kim CI, Koksal E, Li Y, Lipoeto NI, Ma G, Mangialavori GL, Matsumura Y, McGarvey ST, Fen CM, Mensink GB, Koch R, Monge-Rojas R, Musaiger AO, Naska A, Ocke MC, Oltarzewski M, Orfanos P, Ovaskainen ML, Pan WH, Panagiotakos DB, Pekcan GA, Petrova S, Piaseu N, Pitsavos C, Posada LG, Riley LM, Sánchez-Romero LM, Selamat RB, Sharma S, Sibai AM, Sichieri R, Simmala C, Steingrimsdottir L, Sygnowska EH, Szponar L, Tapanainen H, Templeton R, Thanopoulou A, Thorgeirsdóttir H, Thorsdottir I, Trichopoulou A, Tsugane S, Turrini A, Vaask S, Veerman JL, Verena N, Waskiewicz A, Zaghloul S, Zajkás G.
  • Yes, Free full text of study was found:
  2229 Hits

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