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Association of pro-inflammatory diet with increased risk of all-cause dementia and Alzheimer's dementia: a prospective study of 166,377 UK Biobank participants
Generous consumption of pro-inflammatory foods may facilitate the onset of dementia, particularly Alzheimer's disease, in men and women.
This study estimated the risk of dementia associated with the intake of pro-inflammatory foods. Researchers used validated food frequency questionnaires to assess the inflammatory potentials of the diets consumed by 166,377 UK men and women whose mental health was followed over a 9-year period.
Researchers found a high proportion of dementia, particularly Alzheimer's disease, among top consumers of pro-inflammatory foods. This study recognized that following a high inflammatory diet may make an individual more likely to suffer from dementia.
Research Summary Information
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2023
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Yisen Shi, Fabin Lin, Yueping Li, Yingqing Wang, Xiaochun Chen, Fangang Meng, Qinyong Ye, Guoen Cai
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Department of Neurology, Center for Cognitive Neurology, Institute of Clinical Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China. Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, 350001, China. Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China. mengfg@ccmu.edu.cn. Department of Neurology, Center for Cognitive Neurology, Institute of Clinical Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. unionqyye@163.com. Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. unionqyye@163.com. Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China. unionqyye@163.com. Department of Neurology, Center for Cognitive Neurology, Institute of Clinical Neurology, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. cgessmu@126.com. Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, China. cgessmu@126.com. Fujian Key Laboratory of Molecular Neurology, Fujian Medical University, 88 Jiaotong Road, Fuzhou, 350001, China. cgessmu@126.com.
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