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Sugar-sweetened beverage, diet soda, and fatty liver disease in the Framingham Heart Study cohorts.

​Regular drinking of sugar-sweetened beverages may promote the development of fatty liver disease.

This study investigated the effect of high dietary ingestion of diet soda and sugar-sweetened beverages on non-alcoholic fatty liver disease risk. Researchers collated and analyzed data on the sugary drink intake and the incidence of non-alcoholic fatty liver disease among 2,634 men and women recruited from the Framingham Health Study Cohort.

Researchers discovered that generous intake of sugar-sweetened beverages increased the risk of having non-alcoholic fatty liver disease, especially in overweight and obese individuals. On the other hand, regular drinking of diet soda did not have any significant effect on non-alcoholic fatty liver disease risk in this study The findings of this study indicate that habitual consumption of sugar-sweetened beverages may contribute to the high incidence of non-alcoholic fatty liver disease in the general population.

Research Summary Information

  • 2015
  • Ma J, Fox CS, Jacques PF, Speliotes EK3, Hoffmann U, Smith CE, Saltzman E, McKeown NM.
  • USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, United States. NHLBI's Framingham Heart Study, Framingham, MA, United States; Harvard Medical School, Boston, MA, United States. University of Michigan Medical School, Ann Arbor, MI, United States. Harvard Medical School, Boston, MA, United States; Massachusetts General Hospital, Boston, MA, United States. USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, United States. Electronic address: nicola.mckeown@tufts.edu.
  • Yes, Free full text of study was found:
  • No. Source of funding disclosure not found
  • No. Potential conflicts disclosure not found
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