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Gut microbial-dependent trimethylamine-N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
High serum concentrations of TMAO are associated with high incidence of renal disorders and mortality. Dietary choline, lecithin (phosphatidylcholine), and L-carnitine are rich sources of trimethylamine-N-oxide (TMAO). This research work was carried...
https://www.drcarney.com/science/disease-conditions/kidney-disease/gut-microbial-dependent-trimethylamine-n-oxide-tmao-pathway-contributes-to-both-development-of-renal-insufficiency-and-mortality-risk-in-chronic-kidney-disease -
Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure.
Increased dietary exposure to choline, betaine, and trimethylamine-N-oxide (TMAO) predisposes cardiovascular disease patients to adverse cardiac events, such heart failure. Choline, betaine, and phosphatidylchomine are dietary precursors of...
https://www.drcarney.com/science/disease-conditions/cardiovascular-disease/intestinal-microbiota-dependent-phosphatidylcholine-metabolites-diastolic-dysfunction-and-adverse-clinical-outcomes-in-chronic-systolic-heart-failure -
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
High serum and urine concentrations of TMAO, produced from intestinal microbial metabolism of phosphatidylcholine, may increase an individual’s susceptibility to adverse cardiac events and cardiovascular diseases. This study investigated the role of...
https://www.drcarney.com/science/disease-conditions/cardiovascular-disease/intestinal-microbial-metabolism-of-phosphatidylcholine-and-cardiovascular-risk -
Red Meat, Gut Bacteria and Heart Disease
Research indicates that eating red meat increases the risk of death from cardiovascular disease. This is consistent with the results from the Nurses' Health Study and Health Professionals Follow-up study , that involved 120,000 people. It was estimated...
https://www.drcarney.com/blog/science-inspired/red-meat-gut-bacteria-and-heart-disease -
Intestinal microbiota metabolism of L-Carnitine, a nutrient in red meat, promotes atherosclerosis.
Red meat is a major source of L-carnitine, which is metabolized to the pro-atherogenic agent trimethylamine-N-oxide (TMAO) by bacteria in the small intestine. This study examined the relationship between the consumption of dietary L-carnitine and...
https://www.drcarney.com/science/disease-conditions/atherosclerosis/intestinal-microbiota-metabolism-of-l-carnitine-a-nutrient-in-red-meat-promotes-atherosclerosis -
Red Meat Linked to Heart Disease
Research has narrowed down a compound in red meat that could be an important link in the promotion of coronary artery disease. This is in addition to the well known fact that saturated animal fats significantly increase the risk factors associated with...
https://www.drcarney.com/blog/science-inspired/red-meat-linked-to-heart-disease -
Cardiovascular Disease Risk Increased by Red Meat
Consuming animal-based foods containing L-carnitine promotes the development of cardiovascular diseases , such as atherosclerosis, stroke, and myocardial infarction. L-carnitine is a nutrient that helps to transport fatty acids to the mitochondria, the...
https://www.drcarney.com/blog/condition-related/cardiovascular-disease-risk-increased-by-red-meat -
Intestinal microbiota metabolism and atherosclerosis.
Trimethylamine-N-oxide (TMAO), a metabolite produced by intestinal microbes, is associated with elevated atherosclerosis and cardiovascular disease risk. This study evaluated the association between the metabolic activity of intestinal microbes and...
https://www.drcarney.com/science/disease-conditions/atherosclerosis/intestinal-microbiota-metabolism-and-atherosclerosis -
Red Meat Increases Stroke Risk
Some people cherish the taste of a delicious red meat based meal so much that they feel they just can't survive without it. For others... not so much. Those people who belong to the first group should be interested in the findings of a recent study that...
https://www.drcarney.com/blog/condition-related/red-meat-increases-stroke-risk -
Red Meat Increases Stomach Cancer Risk
Numerous studies have examined the impact of diets on incidence of stomach (gastric) cancer, including whether certain foods increase or decrease the risk of this cancer. One food that has been highlighted in these studies is red meat. So the question...
https://www.drcarney.com/blog/condition-related/red-meat-increases-stomach-cancer-risk -
Unscrambling the Truth About Eggs
Are eggs really that "incredible" or are the industry's marketing strategies "incredible?" You might be surprised to learn how big industries use clever marketing strategies to boost the sale of their products. One technique that Dr. John McDougall...
https://www.drcarney.com/articles/unscrambling-the-truth-about-eggs
